Sheep genotyping for PrP gene polymorphisms in rare Greek breeds

نویسندگان

  • Loukia V. Ekateriniadou
  • Cynthia H. Panagiotidis
  • Anastasios Terzis
  • Konstantoula Ploumi
  • Alexandros Triantafyllidis
  • Panagiotis Deligiannidis
  • Costas Triantaphyllidis
  • Theodoros Sklaviadis
  • L. V. Ekateriniadou
چکیده

L. V. Ekateriniadou, PhD, National Agricultural Research Foundation Veterinary Research Institute, 570 08 Ionia, Thessaloniki, Greece C. H. Panagiotidis, PhD, A. Terzis, BA, T. Sklaviadis, PhD Prion Disease Research Group, School of Pharmacy, Aristotle University of Thessaloniki 54 124 Thessaloniki, Greece A. Triantafyllidis, PhD, P. Deligiannidis, MS, C. Triantaphyllidis, PhD, School of Biology, Aristotle University of Thessaloniki 54 124 Thessaloniki, Greece K. Ploumi, DVM, National Agricultural Research Foundation, Agricultural Research Station of Chalkidiki, 63200 Agios Mamas, Greece

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Breeding for resistance to scrapie: Detection of polymorphisms in the prion protein gene in German sheep breeds

Scrapie is a fatal neurodegenerative disease of sheep and goats belonging to the group of transmissible spongiform encephalopathies (TSE). TSEs are characterised by distinctive pathology, the involvement of a hostencoded prion protein (PrP) in disease development and genetic control of susceptibility. Polymorphisms in three different codons of the ovine prion protein (PrP) gene (136, 154, 171) ...

متن کامل

Genotyping of PRNP coding region for scrapie in Indian sheep

Prions are unprecedented infectious pathogens that cause a group of invariably fatal neurodegenerative disease by an entirely novel mechanism. The conformational change in prion proteins results in a change from a predominantly α-helical protein to a β-sheet form, which causes scrapie in sheep and goat. The present study was carried out to identify polymorphisms of the prion protein gene (PrP) ...

متن کامل

Single Nucleotide Polymorphisms (SNPs) of GDF9 Gene in Bahmaei and Lak Ghashghaei Sheep Breeds and Its Association with Litter Size

Growth differentiation factor 9 (GDF9) belong to the superfamily of transforming growth factor β that is highly expressed in growing ovarian follicles of oocyte, and it has been strongly related to fecundity traits in sheep. Therefore, the GDF9 gene could serve as a genetic marker for improvement of reproductive performance in sheep. Therefore, the aim of this study was to invest...

متن کامل

Polymorphism of sheep POU1F1 gene exon 6 and 3'UTR region and their association with milk production traits

The purpose of the study was to detect the AluI and DdeI polymorphisms within POU1F1 gene exon 6 and 3'UTR region in Turkish sheep breeds, and their association with milk productive traits. Jugular blood samples were collected from 50 Sakiz, 50 White Karaman, and 50 Awassi sheep using EDTA as an anticoagulant. PCR-RFLP and sequencing analysis were performed to investigate possible polymorphisms...

متن کامل

Prion protein gene (PrP) polymorphisms in healthy sheep in Turkey.

Scrapie, a transmissible spongiform encephalopathy (TSE) or prion disease, is a fatal, neurodegenerative disease in sheep and goats. This disease has been known in Europe for more than 250 years. Susceptibility to scrapie is associated with polymorphisms in the sheep prion protein gene (PrP) gene. In sheep, polymorphism in the PrP gene has been identified at a number of codons, and polymorphism...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005